1 Semaglutide (Ozempic) FDA-approved treatment for type 2 diabetes mellitus (as Ozempic/Rybelsus) FDA-approved chronic weight management in adults with obesity or overweight with comorbidities (as Wegovy)
2 Tirzepatide (Mounjaro) FDA-approved treatment for type 2 diabetes mellitus (as Mounjaro) FDA-approved for chronic weight management in adults with obesity or overweight with comorbidities (as Zepbound)
3 BPC-157 (Body Protection Compound-157) Accelerating tendon and ligament healing in preclinical models Supporting gastrointestinal mucosal integrity and ulcer healing
4 GLP-1 (Glucagon-Like Peptide-1) Biological template for GLP-1 receptor agonist drugs Natural postprandial blood glucose regulation
5 Oxytocin (Pitocin) FDA-approved for labor induction and augmentation (as Pitocin) Prevention of postpartum hemorrhage
6 Glutathione (GSH) Master antioxidant defense protecting cells from oxidative damage Detoxification support through conjugation of harmful compounds
7 Collagen Peptides (Hydrolyzed Collagen) Oral supplementation for skin hydration, elasticity, and wrinkle reduction Joint health support and osteoarthritis symptom management
8 Liraglutide (Victoza) FDA-approved treatment for type 2 diabetes (as Victoza) FDA-approved for weight management in adults and adolescents 12+ (as Saxenda)
9 TB-500 (Thymosin Beta-4) Promoting wound healing and tissue repair in preclinical research Supporting tendon and ligament recovery in veterinary medicine
10 NAD+ (Nicotinamide Adenine Dinucleotide) Central role in cellular energy production and mitochondrial function DNA repair through PARP enzyme activation
11 GHK-Cu (Copper Peptide) Topical skin rejuvenation including reduction of fine lines and wrinkles Wound healing acceleration and post-procedure skin recovery
12 CJC-1295 (CJC-1295 DAC) Stimulating natural growth hormone secretion from the pituitary gland Anti-aging protocols aimed at optimizing growth hormone and IGF-1 levels
13 Ipamorelin (IPA) Selective stimulation of pituitary growth hormone release Anti-aging protocols for GH optimization with minimal side effects
14 Melanotan II (MT-2) Stimulation of melanogenesis for skin tanning with reduced UV exposure Research into melanocortin system's role in pigmentation
15 PT-141 (Bremelanotide) FDA-approved treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women (as Vyleesi) Researched for male erectile dysfunction, including PDE5 inhibitor non-responders
16 MK-677 (Ibutamoren) Oral stimulation of growth hormone and IGF-1 release Research into age-related GH decline and body composition
17 Sermorelin (Geref) Previously FDA-approved for growth hormone deficiency diagnosis and treatment in children Off-label use for age-related growth hormone decline in adults
18 LL-37 (Cathelicidin) Innate immune defense against bacterial, viral, and fungal pathogens Research into biofilm disruption for chronic infection management
19 Retatrutide (LY3437943) Under clinical development for chronic weight management Investigated for type 2 diabetes treatment
20 GHRP-6 (Growth Hormone Releasing Peptide-6) Potent stimulation of growth hormone release from the pituitary gland Research tool for studying the GHS receptor and ghrelin signaling
21 GHRP-2 (Growth Hormone Releasing Peptide-2) Approved diagnostic agent for GH deficiency evaluation in Japan Potent stimulation of growth hormone release for research purposes
22 AOD-9604 (Advanced Obesity Drug) Investigated for fat metabolism and body composition improvement Studied for stimulating lipolysis without growth-promoting effects
23 Selank (TP-7) Approved anxiolytic treatment in Russia for generalized anxiety Nootropic use for cognitive enhancement and mental clarity
24 Semax (MEHFPGP) Approved in Russia for stroke recovery and cerebral circulation disorders Cognitive enhancement and nootropic applications
25 Tesamorelin (Egrifta) FDA-approved for reduction of excess abdominal fat in HIV-associated lipodystrophy Stimulating natural growth hormone release through pituitary activation
26 Kisspeptin-10 (KP-10) Research into fertility treatment and reproductive hormone stimulation Studied as a safer oocyte maturation trigger in IVF protocols
27 Epithalon (Epitalon) Investigated for telomerase activation and telomere length maintenance Anti-aging research based on potential cellular rejuvenation
28 Thymosin Alpha-1 (Ta1) Approved treatment for hepatitis B in multiple countries Adjunctive treatment for hepatitis C with interferon in multiple countries
29 Hexarelin (Examorelin) Most potent acute GH release among GHRP-class peptides for research purposes Investigated for cardioprotective effects independent of GH release
30 KPV (Alpha-MSH Fragment) Research into inflammatory bowel disease (ulcerative colitis and Crohn's disease) Anti-inflammatory applications through NF-κB pathway inhibition
31 Follistatin 344 (FST-344) Research into myostatin inhibition for muscle growth Investigated for muscular dystrophy treatment via gene therapy
32 DSIP (Delta Sleep-Inducing Peptide) Promotion of restorative delta wave (slow-wave) sleep Research into chronic insomnia and sleep quality improvement
33 IGF-1 LR3 (Long R3 IGF-1) Research into muscle hypertrophy and protein synthesis Cell culture growth factor in laboratory research
34 MGF (Mechano Growth Factor) Research into muscle satellite cell activation and proliferation Investigated for muscle repair and regeneration following injury
35 Humanin (HN) Research into neuroprotection against Alzheimer's disease pathology Investigated for cardiovascular protection from ischemic injury
36 MOTS-c (Mitochondrial-Derived Peptide MOTS-c) Research into metabolic regulation and insulin sensitization Investigated as an exercise mimetic
37 SS-31 (Elamipretide) Clinical trials for Barth syndrome (genetic mitochondrial cardiomyopathy) Investigated for heart failure and cardiac mitochondrial dysfunction
38 Cerebrolysin (FPF 1070) Approved treatment for acute ischemic stroke in many countries Treatment of traumatic brain injury in clinical protocols
39 Dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) Research into cognitive enhancement and synaptogenesis Investigated for neurodegenerative disease models including Alzheimer's
40 Thymalin (Thymus Extract Peptide) Immune system restoration in elderly and immunocompromised individuals Research into thymic function support during age-related involution
41 VIP (Vasoactive Intestinal Peptide) Investigated for Chronic Inflammatory Response Syndrome (CIRS) treatment Studied for pulmonary arterial hypertension
42 Argireline (Acetyl Hexapeptide-3) Topical reduction of facial expression wrinkles Anti-aging skincare formulations as a gentle alternative to neurotoxin injections
43 Matrixyl (Palmitoyl Pentapeptide-4) Stimulation of collagen, elastin, and fibronectin production in the skin Reduction of fine lines and wrinkles through dermal matrix rebuilding
44 Snap-8 (Acetyl Octapeptide-3) Topical reduction of expression lines and wrinkles Cosmetic alternative to injectable neurotoxins for mild lines
45 Pentadecapeptide (PDA) Tissue repair and regeneration research (primarily as BPC-157) Gastrointestinal protection and mucosal healing
46 Orforglipron (LY3502970) Under clinical development for chronic weight management (oral formulation) Investigated for type 2 diabetes treatment as a daily oral medication
47 Survodutide (BI 456906) Clinical development for chronic weight management Investigated for NASH/MASH treatment (liver fat reduction)
48 CagriSema (Cagrilintide/Semaglutide) Under clinical development for chronic weight management Investigated for type 2 diabetes treatment with enhanced weight loss
49 ACE-031 (ActRIIB-Fc) Initially developed for Duchenne muscular dystrophy treatment Research into myostatin/activin pathway inhibition for muscle wasting
50 PE-22-28 (Spadin Analog) Research into novel antidepressant mechanisms via TREK-1 channel blockade Investigated for rapid-onset antidepressant effects in animal models