This website is for informational purposes only and does not constitute medical advice. Read disclaimer
The Definitive Guide to
Peptide Research
Explore the world's most comprehensive peptide database. Detailed profiles with uses, research findings, safety data, and legal status — all ranked by popularity.
150+
Peptides Ranked
30
Categories
22
Blog Articles
500+
Research Sources
Top 3 Most Popular Peptides
The most researched and widely discussed peptides worldwide
Semaglutide
Weight ManagementAn FDA-approved GLP-1 receptor agonist used for type 2 diabetes management and chronic weight management, representing one of the most significant pharmaceutical developments in obesity treatment.
Tirzepatide
Weight ManagementA dual GIP/GLP-1 receptor agonist approved for type 2 diabetes and weight management, demonstrating even greater weight loss efficacy than semaglutide in clinical trials.
BPC-157
Tissue RepairA synthetic peptide derived from a protein found in gastric juice, studied for its regenerative and protective properties across multiple tissue types.
Top 50 Peptides
Ranked by research interest and real-world popularity
| Rank | Peptide | Category | Key Uses | |
|---|---|---|---|---|
| 1 | Semaglutide(Ozempic) | Weight Management | FDA-approved treatment for type 2 diabetes mellitus (as Ozempic/Rybelsus)FDA-approved chronic weight management in adults with obesity or overweight with comorbidities (as Wegovy) | |
| 2 | Tirzepatide(Mounjaro) | Weight Management | FDA-approved treatment for type 2 diabetes mellitus (as Mounjaro)FDA-approved for chronic weight management in adults with obesity or overweight with comorbidities (as Zepbound) | |
| 3 | BPC-157(Body Protection Compound-157) | Tissue Repair | Accelerating tendon and ligament healing in preclinical modelsSupporting gastrointestinal mucosal integrity and ulcer healing | |
| 4 | GLP-1(Glucagon-Like Peptide-1) | Metabolic | Biological template for GLP-1 receptor agonist drugsNatural postprandial blood glucose regulation | |
| 5 | Oxytocin(Pitocin) | Reproductive Health | FDA-approved for labor induction and augmentation (as Pitocin)Prevention of postpartum hemorrhage | |
| 6 | Glutathione(GSH) | Antioxidant | Master antioxidant defense protecting cells from oxidative damageDetoxification support through conjugation of harmful compounds | |
| 7 | Collagen Peptides(Hydrolyzed Collagen) | Cosmetic | Oral supplementation for skin hydration, elasticity, and wrinkle reductionJoint health support and osteoarthritis symptom management | |
| 8 | Liraglutide(Victoza) | Weight Management | FDA-approved treatment for type 2 diabetes (as Victoza)FDA-approved for weight management in adults and adolescents 12+ (as Saxenda) | |
| 9 | TB-500(Thymosin Beta-4) | Tissue Repair | Promoting wound healing and tissue repair in preclinical researchSupporting tendon and ligament recovery in veterinary medicine | |
| 10 | NAD+(Nicotinamide Adenine Dinucleotide) | Antioxidant | Central role in cellular energy production and mitochondrial functionDNA repair through PARP enzyme activation | |
| 11 | GHK-Cu(Copper Peptide) | Skin & Anti-Aging | Topical skin rejuvenation including reduction of fine lines and wrinklesWound healing acceleration and post-procedure skin recovery | |
| 12 | CJC-1295(CJC-1295 DAC) | Growth Hormone | Stimulating natural growth hormone secretion from the pituitary glandAnti-aging protocols aimed at optimizing growth hormone and IGF-1 levels | |
| 13 | Ipamorelin(IPA) | Growth Hormone | Selective stimulation of pituitary growth hormone releaseAnti-aging protocols for GH optimization with minimal side effects | |
| 14 | Melanotan II(MT-2) | Skin & Anti-Aging | Stimulation of melanogenesis for skin tanning with reduced UV exposureResearch into melanocortin system's role in pigmentation | |
| 15 | PT-141(Bremelanotide) | Sexual Health | FDA-approved treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women (as Vyleesi)Researched for male erectile dysfunction, including PDE5 inhibitor non-responders | |
| 16 | MK-677(Ibutamoren) | Growth Hormone | Oral stimulation of growth hormone and IGF-1 releaseResearch into age-related GH decline and body composition | |
| 17 | Sermorelin(Geref) | Growth Hormone | Previously FDA-approved for growth hormone deficiency diagnosis and treatment in childrenOff-label use for age-related growth hormone decline in adults | |
| 18 | LL-37(Cathelicidin) | Immune Support | Innate immune defense against bacterial, viral, and fungal pathogensResearch into biofilm disruption for chronic infection management | |
| 19 | Retatrutide(LY3437943) | Weight Management | Under clinical development for chronic weight managementInvestigated for type 2 diabetes treatment | |
| 20 | GHRP-6(Growth Hormone Releasing Peptide-6) | Growth Hormone | Potent stimulation of growth hormone release from the pituitary glandResearch tool for studying the GHS receptor and ghrelin signaling | |
| 21 | GHRP-2(Growth Hormone Releasing Peptide-2) | Growth Hormone | Approved diagnostic agent for GH deficiency evaluation in JapanPotent stimulation of growth hormone release for research purposes | |
| 22 | AOD-9604(Advanced Obesity Drug) | Weight Management | Investigated for fat metabolism and body composition improvementStudied for stimulating lipolysis without growth-promoting effects | |
| 23 | Selank(TP-7) | Neuroprotective | Approved anxiolytic treatment in Russia for generalized anxietyNootropic use for cognitive enhancement and mental clarity | |
| 24 | Semax(MEHFPGP) | Neuroprotective | Approved in Russia for stroke recovery and cerebral circulation disordersCognitive enhancement and nootropic applications | |
| 25 | Tesamorelin(Egrifta) | Growth Hormone | FDA-approved for reduction of excess abdominal fat in HIV-associated lipodystrophyStimulating natural growth hormone release through pituitary activation | |
| 26 | Kisspeptin-10(KP-10) | Reproductive Health | Research into fertility treatment and reproductive hormone stimulationStudied as a safer oocyte maturation trigger in IVF protocols | |
| 27 | Epithalon(Epitalon) | Skin & Anti-Aging | Investigated for telomerase activation and telomere length maintenanceAnti-aging research based on potential cellular rejuvenation | |
| 28 | Thymosin Alpha-1(Ta1) | Immune Support | Approved treatment for hepatitis B in multiple countriesAdjunctive treatment for hepatitis C with interferon in multiple countries | |
| 29 | Hexarelin(Examorelin) | Growth Hormone | Most potent acute GH release among GHRP-class peptides for research purposesInvestigated for cardioprotective effects independent of GH release | |
| 30 | KPV(Alpha-MSH Fragment) | Immune Support | Research into inflammatory bowel disease (ulcerative colitis and Crohn's disease)Anti-inflammatory applications through NF-κB pathway inhibition | |
| 31 | Follistatin 344(FST-344) | Muscle Growth | Research into myostatin inhibition for muscle growthInvestigated for muscular dystrophy treatment via gene therapy | |
| 32 | DSIP(Delta Sleep-Inducing Peptide) | Sleep & Recovery | Promotion of restorative delta wave (slow-wave) sleepResearch into chronic insomnia and sleep quality improvement | |
| 33 | IGF-1 LR3(Long R3 IGF-1) | Muscle Growth | Research into muscle hypertrophy and protein synthesisCell culture growth factor in laboratory research | |
| 34 | MGF(Mechano Growth Factor) | Muscle Growth | Research into muscle satellite cell activation and proliferationInvestigated for muscle repair and regeneration following injury | |
| 35 | Humanin(HN) | Mitochondrial | Research into neuroprotection against Alzheimer's disease pathologyInvestigated for cardiovascular protection from ischemic injury | |
| 36 | MOTS-c(Mitochondrial-Derived Peptide MOTS-c) | Mitochondrial | Research into metabolic regulation and insulin sensitizationInvestigated as an exercise mimetic | |
| 37 | SS-31(Elamipretide) | Mitochondrial | Clinical trials for Barth syndrome (genetic mitochondrial cardiomyopathy)Investigated for heart failure and cardiac mitochondrial dysfunction | |
| 38 | Cerebrolysin(FPF 1070) | Neuroprotective | Approved treatment for acute ischemic stroke in many countriesTreatment of traumatic brain injury in clinical protocols | |
| 39 | Dihexa(N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) | Cognitive Enhancement | Research into cognitive enhancement and synaptogenesisInvestigated for neurodegenerative disease models including Alzheimer's | |
| 40 | Thymalin(Thymus Extract Peptide) | Immune Support | Immune system restoration in elderly and immunocompromised individualsResearch into thymic function support during age-related involution | |
| 41 | VIP(Vasoactive Intestinal Peptide) | Immune Support | Investigated for Chronic Inflammatory Response Syndrome (CIRS) treatmentStudied for pulmonary arterial hypertension | |
| 42 | Argireline(Acetyl Hexapeptide-3) | Cosmetic | Topical reduction of facial expression wrinklesAnti-aging skincare formulations as a gentle alternative to neurotoxin injections | |
| 43 | Matrixyl(Palmitoyl Pentapeptide-4) | Cosmetic | Stimulation of collagen, elastin, and fibronectin production in the skinReduction of fine lines and wrinkles through dermal matrix rebuilding | |
| 44 | Snap-8(Acetyl Octapeptide-3) | Cosmetic | Topical reduction of expression lines and wrinklesCosmetic alternative to injectable neurotoxins for mild lines | |
| 45 | Pentadecapeptide(PDA) | Tissue Repair | Tissue repair and regeneration research (primarily as BPC-157)Gastrointestinal protection and mucosal healing | |
| 46 | Orforglipron(LY3502970) | Weight Management | Under clinical development for chronic weight management (oral formulation)Investigated for type 2 diabetes treatment as a daily oral medication | |
| 47 | Survodutide(BI 456906) | Weight Management | Clinical development for chronic weight managementInvestigated for NASH/MASH treatment (liver fat reduction) | |
| 48 | CagriSema(Cagrilintide/Semaglutide) | Weight Management | Under clinical development for chronic weight managementInvestigated for type 2 diabetes treatment with enhanced weight loss | |
| 49 | ACE-031(ActRIIB-Fc) | Muscle Growth | Initially developed for Duchenne muscular dystrophy treatmentResearch into myostatin/activin pathway inhibition for muscle wasting | |
| 50 | PE-22-28(Spadin Analog) | Cognitive Enhancement | Research into novel antidepressant mechanisms via TREK-1 channel blockadeInvestigated for rapid-onset antidepressant effects in animal models |
Semaglutide
Weight ManagementAn FDA-approved GLP-1 receptor agonist used for type 2 diabetes management and chronic weight management, representing one of the most significant pharmaceutical developments in obesity treatment.
Tirzepatide
Weight ManagementA dual GIP/GLP-1 receptor agonist approved for type 2 diabetes and weight management, demonstrating even greater weight loss efficacy than semaglutide in clinical trials.
BPC-157
Tissue RepairA synthetic peptide derived from a protein found in gastric juice, studied for its regenerative and protective properties across multiple tissue types.
GLP-1
MetabolicThe naturally occurring incretin hormone that regulates blood sugar and appetite, serving as the biological template for the revolutionary GLP-1 receptor agonist drug class.
Oxytocin
Reproductive HealthA naturally occurring neuropeptide hormone with established roles in childbirth, lactation, and social bonding, increasingly studied for autism, anxiety, and social cognition.
Glutathione
AntioxidantA tripeptide antioxidant produced in every cell of the body, considered the master antioxidant for its central role in detoxification, immune function, and protection against oxidative stress.
Collagen Peptides
CosmeticBioactive peptide fragments derived from collagen protein hydrolysis, among the most widely consumed supplements globally for skin, joint, and bone health support.
Liraglutide
Weight ManagementAn FDA-approved GLP-1 receptor agonist for type 2 diabetes and weight management, predating semaglutide as the first GLP-1 agonist approved specifically for obesity.
TB-500
Tissue RepairA synthetic version of a naturally occurring peptide involved in tissue repair, cell migration, and anti-inflammatory processes, widely used in research and veterinary applications.
NAD+
AntioxidantA critical coenzyme found in every living cell that plays essential roles in energy metabolism, DNA repair, and cellular signaling, with declining levels associated with aging and age-related diseases.
GHK-Cu
Skin & Anti-AgingA naturally occurring copper-binding tripeptide with broad regenerative properties, extensively used in skincare and studied for wound healing, anti-aging, and tissue remodeling.
CJC-1295
Growth HormoneA synthetic growth hormone-releasing hormone (GHRH) analog that stimulates pituitary growth hormone secretion, available in two forms with different duration profiles.
Ipamorelin
Growth HormoneA selective growth hormone secretagogue peptide that stimulates GH release with minimal impact on cortisol and prolactin, considered one of the milder GH-releasing peptides.
Melanotan II
Skin & Anti-AgingA synthetic melanocortin peptide that stimulates melanogenesis for skin tanning, also noted for effects on sexual arousal and appetite suppression.
PT-141
Sexual HealthA melanocortin receptor agonist FDA-approved for hypoactive sexual desire disorder in premenopausal women, acting through central nervous system pathways rather than vascular mechanisms.
MK-677
Growth HormoneAn orally active growth hormone secretagogue that mimics ghrelin to stimulate GH and IGF-1 release, notable for being a non-peptide small molecule rather than an injectable peptide.
Sermorelin
Growth HormoneA synthetic analog of growth hormone-releasing hormone (GHRH) that was previously FDA-approved for diagnosing and treating growth hormone deficiency in children.
LL-37
Immune SupportThe only human cathelicidin antimicrobial peptide, playing a critical role in innate immune defense against bacteria, viruses, and fungi, with additional immunomodulatory and wound healing properties.
Retatrutide
Weight ManagementA triple-acting agonist targeting GIP, GLP-1, and glucagon receptors simultaneously, representing the next evolution in incretin-based obesity treatment with the highest weight loss observed in clinical trials to date.
GHRP-6
Growth HormoneOne of the first synthetic growth hormone secretagogues discovered, known for potent GH release but also significant appetite stimulation through ghrelin receptor activation.
GHRP-2
Growth HormoneA synthetic growth hormone secretagogue considered more potent than GHRP-6 with less appetite stimulation, approved in Japan for diagnostic evaluation of GH deficiency.
AOD-9604
Weight ManagementA modified fragment of human growth hormone specifically studied for fat metabolism, designed to retain lipolytic properties without the growth-promoting or diabetogenic effects of full GH.
Selank
NeuroprotectiveA synthetic analog of the naturally occurring immunomodulatory peptide tuftsin, developed in Russia as an anxiolytic and nootropic agent with a unique mechanism distinct from benzodiazepines.
Semax
NeuroprotectiveA synthetic analog of ACTH(4-10) developed in Russia as a neuroprotective and nootropic agent, approved there for stroke recovery, cognitive disorders, and peptic ulcer treatment.
Tesamorelin
Growth HormoneAn FDA-approved GHRH analog specifically indicated for reducing excess abdominal fat in HIV-associated lipodystrophy, also studied for broader metabolic and cognitive benefits.
Kisspeptin-10
Reproductive HealthA truncated form of the naturally occurring hormone kisspeptin that plays a master regulatory role in reproductive function, studied for fertility applications and hormonal assessment.
Epithalon
Skin & Anti-AgingA synthetic tetrapeptide studied for its potential to activate telomerase, the enzyme responsible for maintaining telomere length, based on decades of research by Russian gerontologist Vladimir Khavinson.
Thymosin Alpha-1
Immune SupportA naturally occurring thymic peptide that is one of the most clinically validated immune-modulating peptides, approved in multiple countries for hepatitis B/C and as an immune system adjuvant.
Hexarelin
Growth HormoneThe most potent synthetic growth hormone secretagogue in the GHRP family, known for robust GH release and cardioprotective properties, but also notable for causing desensitization with prolonged use.
KPV
Immune SupportA tripeptide fragment of alpha-melanocyte-stimulating hormone with potent anti-inflammatory properties, studied for inflammatory bowel conditions and skin inflammation.
Follistatin 344
Muscle GrowthA naturally occurring glycoprotein that inhibits myostatin and activin, studied for its potential to promote muscle growth beyond normal genetic limits.
DSIP
Sleep & RecoveryA naturally occurring nonapeptide first isolated from rabbit brain tissue during induced sleep, studied for its role in sleep regulation, stress adaptation, and neuroendocrine modulation.
IGF-1 LR3
Muscle GrowthA modified form of IGF-1 with enhanced potency and a significantly longer half-life, widely studied for muscle growth and cell proliferation effects.
MGF
Muscle GrowthA splice variant of IGF-1 produced in response to mechanical stress on muscle tissue, studied for its role in muscle repair and satellite cell activation.
Humanin
MitochondrialA mitochondrial-derived peptide with cytoprotective properties, studied for its potential to protect against age-related diseases including Alzheimer's, cardiovascular disease, and metabolic disorders.
MOTS-c
MitochondrialA mitochondrial-derived peptide that acts as an exercise mimetic, regulating metabolic homeostasis with potential applications in aging, obesity, and metabolic disease.
SS-31
MitochondrialA mitochondria-targeted peptide that concentrates in the inner mitochondrial membrane, studied for its ability to improve mitochondrial function in aging and disease states.
Cerebrolysin
NeuroprotectiveA complex of neurotrophic peptides derived from porcine brain tissue, approved in many countries for stroke, traumatic brain injury, and dementia, with extensive clinical use particularly in Europe and Asia.
Dihexa
Cognitive EnhancementA synthetic peptide derivative of angiotensin IV reported to be millions of times more potent than BDNF at promoting new synaptic connections, studied for cognitive enhancement and neurodegenerative diseases.
Thymalin
Immune SupportA peptide bioregulator derived from thymus gland extract, studied in Russia for immune restoration and anti-aging effects, particularly in elderly populations with declining thymic function.
VIP
Immune SupportA naturally occurring 28-amino acid neuropeptide with potent anti-inflammatory, vasodilatory, and immunoregulatory properties, studied for chronic inflammatory response syndrome and respiratory conditions.
Argireline
CosmeticOne of the first and most commercially successful cosmetic peptides, designed to reduce wrinkles by partially inhibiting neurotransmitter release at the facial neuromuscular junction.
Matrixyl
CosmeticA lipopeptide that stimulates collagen production by mimicking the body's natural collagen-building signals, one of the most proven and widely used anti-aging cosmetic peptides.
Snap-8
CosmeticA synthetic octapeptide designed to reduce facial wrinkles by mimicking the mechanism of botulinum toxin, inhibiting the SNARE complex involved in muscle contraction at the neuromuscular junction.
Pentadecapeptide
Tissue RepairA general class of peptides consisting of 15 amino acids, most notably associated with BPC-157, studied for broad tissue-protective and regenerative properties.
Orforglipron
Weight ManagementA non-peptide, orally available GLP-1 receptor agonist that could revolutionize obesity and diabetes treatment by eliminating the need for injections, in advanced clinical development by Eli Lilly.
Survodutide
Weight ManagementA dual GLP-1 and glucagon receptor agonist being developed for obesity and NASH, offering a different dual-agonist approach from tirzepatide by targeting glucagon rather than GIP alongside GLP-1.
CagriSema
Weight ManagementA combination therapy pairing the amylin analog cagrilintide with semaglutide, designed to provide complementary appetite-suppressing mechanisms for enhanced weight loss.
ACE-031
Muscle GrowthA soluble form of the activin type IIB receptor that acts as a myostatin trap, initially developed for Duchenne muscular dystrophy before clinical development was halted due to safety concerns.
PE-22-28
Cognitive EnhancementA synthetic heptapeptide derived from the sortilin propeptide that acts as a TREK-1 potassium channel blocker, studied as a rapid-acting antidepressant with fewer side effects than traditional antidepressants.
Browse by Category
Find peptides by their primary area of research
Why 50 Best Peptides?
We provide the most comprehensive, research-backed peptide database on the internet. Every profile is carefully compiled from scientific literature to give you accurate, balanced information.
Research-Based Profiles
Every peptide entry is backed by published scientific research and clinical studies.
Popularity Rankings
Peptides ranked by real-world usage and research interest to prioritize your learning.
Complete Safety Data
Comprehensive risk profiles, side effects, and legal status for every peptide.